HitPredict

Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: TBR1 (Q16650)
T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56)
Gene: TBR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 770 Hs			1 682
+	Hs
		980935 TLE4_HUMAN (1-770): 0: 562: 86.27		TBR1_HUMAN (1-682): 0: 724: 100.00
+	Hs
		980761 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		TBR1_HUMAN (1-682): 0: 724: 100.00
+	Hs
		993440 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		TBR1_HUMAN (1-682): 0: 724: 100.00
+	Hs
		171017 TLE1_HUMAN (1-770): 0: 594: 100.00		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Hs
		980667 TLE1_HUMAN (1-770): 0: 594: 100.00		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		980849 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		TBX15_HUMAN (114-668): 2.6e-132: 404: 24.20
+	Hs
		168131 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		TBX3_HUMAN (116-635): 2.95e-127: 395: 23.44
+	Hs
		171019 TLE4_HUMAN (1-770): 0: 562: 86.27		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Hs
		203427 TLE1_HUMAN (1-770): 0: 594: 100.00		TBX1_HUMAN (180-430): 2.23e-103: 322: 37.95
+	Hs
		980958 TLE4_HUMAN (1-770): 0: 562: 86.27		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		171018 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Hs
		980911 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Dm
		558401 GROU_DROME (1-770): 7.74e-141: 433: 59.79		Q9VMR2_DROME (162-591): 8.5e-94: 303: 26.91
+	Hs
		1132995 Q5T3G3_HUMAN (1-232): 2.89e-127: 381: 95.87		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		168132 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		TBX3_HUMAN (116-635): 2.95e-127: 395: 23.44
+	Hs
		1127614 Q5JSZ1_HUMAN (1-205): 4.02e-109: 333: 78.90		TBX20_HUMAN (106-529): 5.5e-112: 346: 26.17
+	Hs
		171021 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		TBXT_HUMAN (163-621): 4.21e-116: 356: 27.16
+	Hs
		327890 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		TBX6_HUMAN (119-520): 1.63e-103: 324: 30.88
+	Ce
		137656 UNC37_CAEEL (18-684): 5.47e-79: 267: 19.06		TBX1_CAEEL (204-395): 5.75e-95: 295: 44.85
+	Ce
		137670 UNC37_CAEEL (18-684): 5.47e-79: 267: 19.06		TBX12_CAEEL (177-463): 7.29e-91: 288: 34.75