HitPredict

Interactor 1: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Interactor 2: ELF5 (Q9UKW6)
ETS-related transcription factor Elf-5 (E74-like factor 5) (Epithelium-restricted ESE-1-related Ets factor) (Epithelium-specific Ets transcription factor 2) (ESE-2)
Gene: ELF5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 770 Hs			1 265
+	Hs
		794534 TLE1_HUMAN (1-770): 0: 594: 100.00		ETV4_HUMAN (112-260): 1.52e-40: 147: 24.50
+	Hs
		980640 TLE1_HUMAN (1-770): 0: 594: 100.00		FEV_HUMAN (155-255): 1.2e-41: 144: 32.35
+	Hs
		980949 TLE4_HUMAN (1-770): 0: 562: 86.27		FEV_HUMAN (155-255): 1.2e-41: 144: 32.35
+	Hs
		507403 TLE1_HUMAN (1-770): 0: 594: 100.00		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		980853 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		FEV_HUMAN (155-255): 1.2e-41: 144: 32.35
+	Hs
		507404 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Hs
		542002 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		ETS1_HUMAN (22-167): 3.12e-27: 110: 17.69
+	Hs
		993646 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		ELF5_HUMAN (1-265): 1.43e-113: 329: 100.00
+	Hs
		781618 TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42		ETV6_HUMAN (175-255): 1.19e-14: 75.1: 45.12
+	Dm
		558359 GROU_DROME (1-770): 7.74e-141: 433: 59.79		ETS3_DROME (123-255): 2.67e-44: 157: 27.21
+	Hs
		1309167 TBL1Y_HUMAN (569-769): 9.88e-45: 170: 16.06		ELF5_HUMAN (1-265): 1.43e-113: 329: 100.00
+	Hs
		993566 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		FEV_HUMAN (155-255): 1.2e-41: 144: 32.35
+	Hs
		507408 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		ERG_HUMAN (36-141): 5.06e-27: 110: 23.36
+	Ce
		106121 UNC37_CAEEL (18-684): 5.47e-79: 267: 19.06		G5EDL0_CAEEL (173-253): 2.8e-34: 129: 45.12
+	Hs
		840370 TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50		ERF_HUMAN (174-256): 2.19e-12: 68.6: 41.67
+	Hs
		840414 TBL1R_HUMAN (558-769): 4.54e-47: 177: 15.65		ERF_HUMAN (174-256): 2.19e-12: 68.6: 41.67
+	Hs
		781654 TBL1Y_HUMAN (569-769): 9.88e-45: 170: 16.06		ETV6_HUMAN (175-255): 1.19e-14: 75.1: 45.12
+	Hs
		245579 TBL1X_HUMAN (569-769): 5.32e-46: 175: 16.51		ERF_HUMAN (174-256): 2.19e-12: 68.6: 41.67
+	Hs
		781217 TBL1Y_HUMAN (569-769): 9.88e-45: 170: 16.06		ETV3_HUMAN (174-256): 3.77e-13: 70.5: 41.67
+	Hs
		840410 TBL1Y_HUMAN (569-769): 9.88e-45: 170: 16.06		ERF_HUMAN (174-256): 2.19e-12: 68.6: 41.67