HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: FOXL1 (Q12952)
Forkhead box protein L1 (Forkhead-related protein FKHL11) (Forkhead-related transcription factor 7) (FREAC-7)
Gene: FOXL1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25609649, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 772 Hs			1 345
+	Hs
		980596 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		980931 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		FOXL1_HUMAN (1-345): 1.46e-108: 322: 100.00
+	Hs
		877704 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27
+	Hs
		877703 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXA1_HUMAN (5-320): 1.41e-80: 255: 30.27
+	Hs
		980740 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXC1_HUMAN (9-280): 1.15e-53: 186: 35.86
+	Hs
		877992 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Hs
		980855 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980741 TLE3_HUMAN (1-772): 0: 583: 100.00		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Hs
		877602 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXG1_HUMAN (48-224): 2.13e-52: 182: 40.68
+	Hs
		980669 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXA2_HUMAN (7-320): 8.22e-53: 182: 29.13
+	Hs
		877990 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Hs
		980641 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980595 TLE1_HUMAN (1-772): 0: 538: 77.42		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Hs
		980951 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		FOXB1_HUMAN (38-315): 6.26e-51: 173: 29.14
+	Hs
		980930 TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65		FOXI1_HUMAN (6-234): 5.98e-50: 172: 35.02
+	Rn
		88552 D3ZCM7_RAT (1-772): 3.17e-177: 528: 77.94		FOXG1_RAT (5-224): 1.63e-50: 176: 33.64
+	Mm
		1141982 TLE1_MOUSE (1-772): 1.82e-174: 522: 78.22		FOXG1_MOUSE (5-224): 1.31e-50: 176: 33.64
+	Hs
		877991 TLE2_HUMAN (1-772): 4.46e-145: 445: 62.10		FOXA3_HUMAN (47-146): 1.57e-50: 173: 63.00
+	Dm
		558388 GROU_DROME (1-772): 4.17e-136: 421: 57.20		Q961V5_DROME (33-187): 3.17e-48: 166: 42.58
+	Dm
		558360 GROU_DROME (1-772): 4.17e-136: 421: 57.20		SLP1_DROME (33-187): 1.16e-47: 165: 43.23