HitPredict

Interactor 1: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Interactor 2: HTF4 (Q99081)
Transcription factor 12 (TCF-12) (Class B basic helix-loop-helix protein 20) (bHLHb20) (DNA-binding protein HTF4) (E-box-binding protein) (Transcription factor HTF-4)
Gene: TCF12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 772 Hs			1 682
+	Hs
		551125 TLE3_HUMAN (1-772): 0: 583: 100.00		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Hs
		551507 TLE3_HUMAN (1-772): 0: 583: 100.00		TFE2_HUMAN (2-682): 0: 753: 48.93
+	Hs
		551124 TLE1_HUMAN (1-772): 0: 538: 77.42		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Hs
		551506 TLE1_HUMAN (1-772): 0: 538: 77.42		TFE2_HUMAN (2-682): 0: 753: 48.93
+	Hs
		1022858 STRN3_HUMAN (119-770): 2.29e-48: 185: 10.91		HTF4_HUMAN (1-682): 0: 921: 100.00
+	Hs
		551129 TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19		ITF2_HUMAN (2-682): 0: 777: 62.01
+	Hs
		1288259 SNR40_HUMAN (509-677): 5.35e-09: 60.8: 26.52		HTF4_HUMAN (1-682): 0: 921: 100.00
+	Mm
		550260 TLE6_MOUSE (473-772): 7.97e-46: 174: 33.66		TFE2_MOUSE (1-682): 0: 732: 49.43