HitPredict

Interactor 1: RELB (Q04863)
Transcription factor RelB
Gene: RELB

Interactor 2: IKBA (Q9Z1E3)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha)
Gene: Nfkbia

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	15470505, 23086447
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~RHD_dimer
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0007249 - canonical NF-kappaB signal transduction GO:0038061 - non-canonical NF-kappaB signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 558 Mm			1 314
+	Hs
		639731 RELB_HUMAN (1-558): 0: 669: 88.12		IKBA_HUMAN (1-314): 4.98e-78: 242: 91.17
+	Mm
		222602 RELB_MOUSE (1-558): 0: 665: 100.00		IKBE_MOUSE (3-312): 2.9e-74: 234: 31.66
+	Hs
		961365 RELB_HUMAN (1-558): 0: 669: 88.12		NFKB2_HUMAN (68-294): 2.85e-63: 216: 33.48
+	Mm
		981549 RELB_MOUSE (1-558): 0: 665: 100.00		NFKB2_MOUSE (69-297): 5.09e-61: 210: 33.75
+	Hs
		121584 RELB_HUMAN (1-558): 0: 669: 88.12		IKBE_HUMAN (30-220): 8.64e-22: 97: 22.22
+	Mm
		638450 RELB_MOUSE (1-558): 0: 665: 100.00		NFKB1_MOUSE (36-196): 1.61e-21: 97: 21.47
+	Hs
		964488 RELB_HUMAN (1-558): 0: 669: 88.12		IKBB_HUMAN (139-275): 1.75e-14: 75: 20.11
+	Hs
		587532 RELB_HUMAN (1-558): 0: 669: 88.12		NFKB1_HUMAN (21-157): 4.13e-13: 72: 24.31
+	Rn
		1144369 Q7TQN4_RAT (90-528): 4.56e-156: 459: 40.36		IKBA_RAT (1-314): 7.49e-82: 252: 98.73
+	Mm
		978991 TF65_MOUSE (90-528): 4.21e-155: 456: 40.82		IKBA_MOUSE (1-314): 1.29e-81: 251: 100.00
+	Mm
		546810 REL_MOUSE (103-530): 2.34e-151: 448: 39.78		IKBA_MOUSE (1-314): 1.29e-81: 251: 100.00
+	Mm
		222601 TF65_MOUSE (90-528): 4.21e-155: 456: 40.82		IKBE_MOUSE (3-312): 2.9e-74: 234: 31.66
+	Xl
		981811 TF65_XENLA (94-491): 4.79e-155: 455: 41.32		Q6DCW3_XENLA (4-312): 3.07e-75: 235: 58.97
+	Mm
		978989 TF65_MOUSE (90-528): 4.21e-155: 456: 40.82		NFKB2_MOUSE (69-297): 5.09e-61: 210: 33.75
+	Mm
		638449 TF65_MOUSE (90-528): 4.21e-155: 456: 40.82		NFKB1_MOUSE (36-196): 1.61e-21: 97: 21.47
+	Mm
		546805 REL_MOUSE (103-530): 2.34e-151: 448: 39.78		NFKB1_MOUSE (36-196): 1.61e-21: 97: 21.47
+	Hs
		121586 REL_HUMAN (103-530): 1.27e-150: 447: 35.02		IKBE_HUMAN (30-220): 8.64e-22: 97: 22.22
+	Mm
		978962 TF65_MOUSE (90-528): 4.21e-155: 456: 40.82		IKBB_MOUSE (139-275): 5.78e-13: 70.4: 20.11
+	Hs
		587543 REL_HUMAN (103-530): 1.27e-150: 447: 35.02		NFKB1_HUMAN (21-157): 4.13e-13: 72: 24.31
+	Mm
		546808 REL_MOUSE (103-530): 2.34e-151: 448: 39.78		IKBB_MOUSE (139-275): 5.78e-13: 70.4: 20.11