HitPredict

Interactor 1: REL (Q04864)
Proto-oncogene c-Rel
Gene: REL

Interactor 2: IKBD (Q8NI38)
NF-kappa-B inhibitor delta (NFKB inhibitor delta) (I-kappa-B-delta) (IkB-delta) (IkappaBdelta) (IkappaBNS) (T-cell activation NFKB-like protein) (TA-NFKBH)
Gene: NFKBID

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ank_2~RHD_dimer
Common GO terms	GO:0005634 - nucleus GO:0006954 - inflammatory response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 619 Hs			1 313
+	Hs
		587543 REL_HUMAN (1-619): 0: 692: 100.00		NFKB1_HUMAN (160-307): 2.1e-12: 69.8: 26.32
+	Hs
		961369 REL_HUMAN (1-619): 0: 692: 100.00		NFKB2_HUMAN (183-311): 7.93e-12: 67.8: 24.81
+	Hs
		639734 REL_HUMAN (1-619): 0: 692: 100.00		IKBA_HUMAN (47-228): 7.74e-11: 63.9: 30.57
+	Hs
		121586 REL_HUMAN (1-619): 0: 692: 100.00		IKBE_HUMAN (118-305): 8.98e-10: 61.3: 22.05
+	Hs
		978883 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		IKBZ_HUMAN (26-309): 2.66e-88: 280: 42.14
+	Mm
		546805 REL_MOUSE (1-619): 0: 628: 70.19		NFKB1_MOUSE (189-308): 2.16e-12: 69.8: 30.33
+	Mm
		222601 TF65_MOUSE (2-576): 1.99e-167: 490: 38.89		IKBE_MOUSE (73-305): 8.49e-21: 93.3: 22.13
+	Mm
		638472 NFKB1_MOUSE (1-414): 1.82e-152: 465: 33.56		IKBZ_MOUSE (1-182): 1.47e-24: 105: 15.60
+	Mm
		638449 TF65_MOUSE (2-576): 1.99e-167: 490: 38.89		NFKB1_MOUSE (189-308): 2.16e-12: 69.8: 30.33
+	Mm
		978989 TF65_MOUSE (2-576): 1.99e-167: 490: 38.89		NFKB2_MOUSE (26-159): 3.43e-09: 59.8: 23.13
+	Rn
		1144369 Q7TQN4_RAT (2-576): 2.12e-167: 490: 38.48		IKBA_RAT (47-228): 1.8e-09: 59.7: 28.88
+	Hs
		587542 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		NFKB1_HUMAN (160-307): 2.1e-12: 69.8: 26.32
+	Mm
		638435 NFKB1_MOUSE (1-414): 1.82e-152: 465: 33.56		NFKB1_MOUSE (189-308): 2.16e-12: 69.8: 30.33
+	Hs
		961368 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		NFKB2_HUMAN (183-311): 7.93e-12: 67.8: 24.81
+	Hs
		639733 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		IKBA_HUMAN (47-228): 7.74e-11: 63.9: 30.57
+	Hs
		276172 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		PSD10_HUMAN (82-293): 1.11e-10: 62.4: 29.11
+	Hs
		121585 TF65_HUMAN (2-576): 4.74e-158: 466: 37.89		IKBE_HUMAN (118-305): 8.98e-10: 61.3: 22.05
+	Mm
		638473 NFKB1_MOUSE (1-414): 1.82e-152: 465: 33.56		NFKB2_MOUSE (26-159): 3.43e-09: 59.8: 23.13
+	Hs
		276140 NFKB1_HUMAN (1-375): 2e-145: 447: 37.47		PSD10_HUMAN (82-293): 1.11e-10: 62.4: 29.11
+	Hs
		121567 NFKB1_HUMAN (1-375): 2e-145: 447: 37.47		IKBE_HUMAN (118-305): 8.98e-10: 61.3: 22.05