HitPredict

Interactor 1: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Interactor 2: KLK15 (Q9H2R5)
Kallikrein-15 (EC 3.4.21.-) (ACO protease)
Gene: KLK15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1400 Hs			1 256
+	Hs
		441530 MET_HUMAN (1-1391): 0: 1065: 32.44		TM11B_HUMAN (12-252): 2.35e-92: 279: 33.33
+	Hs
		428666 EPHA3_HUMAN (568-1377): 1.49e-169: 535: 16.39		TRY1_HUMAN (1-256): 5.08e-121: 346: 42.25
+	Hs
		1072534 EPHA7_HUMAN (557-1372): 5.26e-172: 542: 17.56		TM11B_HUMAN (12-252): 2.35e-92: 279: 33.33
+	Hs
		872513 EPHB4_HUMAN (557-1371): 7.44e-161: 511: 18.65		TMPS3_HUMAN (4-256): 1.1e-101: 305: 30.45
+	Hs
		409508 EPHB4_HUMAN (557-1371): 7.44e-161: 511: 18.65		HEPS_HUMAN (4-254): 5.24e-98: 294: 30.55
+	Hs
		428664 EPHA1_HUMAN (727-1375): 8.38e-134: 438: 23.79		TRY1_HUMAN (1-256): 5.08e-121: 346: 42.25
+	Hs
		420736 FGFR3_HUMAN (1015-1400): 5.83e-114: 379: 32.20		KLK1_HUMAN (1-256): 2.74e-106: 309: 37.64
+	Hs
		426509 FGFR3_HUMAN (1015-1400): 5.83e-114: 379: 32.20		KLK3_HUMAN (1-256): 3.21e-104: 304: 40.00
+	Hs
		1329636 PLXA1_HUMAN (382-925): 4.04e-43: 174: 21.99		KLK15_HUMAN (1-256): 3.74e-114: 329: 100.00
+	Hs
		435809 IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93		KLK5_HUMAN (13-256): 5.32e-98: 290: 41.46
+	Hs
		435683 IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93		TM11B_HUMAN (12-252): 2.35e-92: 279: 33.33
+	Hs
		411419 INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73		TM11B_HUMAN (12-252): 2.35e-92: 279: 33.33
+	Hs
		433862 LYN_HUMAN (1088-1357): 6.87e-51: 190: 39.11		TM11B_HUMAN (12-252): 2.35e-92: 279: 33.33
+	Hs
		426515 PLXA3_HUMAN (375-943): 1.56e-37: 156: 21.35		KLK3_HUMAN (1-256): 3.21e-104: 304: 40.00
+	Hs
		165175 PLXB2_HUMAN (508-1070): 7.22e-25: 115: 19.34		TMPS3_HUMAN (4-256): 1.1e-101: 305: 30.45
+	Hs
		987312 TYRO3_HUMAN (1062-1348): 1.01e-59: 224: 41.95		KLK4_HUMAN (21-254): 2.08e-52: 172: 38.30
+	Hs
		165219 PLXB2_HUMAN (508-1070): 7.22e-25: 115: 19.34		TM11B_HUMAN (12-252): 2.35e-92: 279: 33.33
+	Mm
		371815 UFO_MOUSE (1062-1348): 4.1e-57: 216: 41.14		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40
+	Mm
		371769 PLXA1_MOUSE (382-925): 1.75e-42: 173: 21.48		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40
+	Mm
		71302 PLXB2_MOUSE (500-799): 1.36e-23: 111: 24.37		CFAD_MOUSE (12-256): 1.1e-45: 155: 37.40