HitPredict

Interactor 1: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16740632
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019899 - enzyme binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1400 Hs			1 303
+	Hs
		981923 RON_HUMAN (19-1400): 0: 1277: 100.00		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Hs
		441587 MET_HUMAN (1-1391): 0: 1065: 32.44		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		609610 FGFR3_HUMAN (1015-1400): 5.83e-114: 379: 32.20		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		983691 FAK1_HUMAN (1022-1395): 3.19e-104: 359: 30.73		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		609537 FGFR3_HUMAN (1015-1400): 5.83e-114: 379: 32.20		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Mm
		710144 FAK1_MOUSE (1022-1395): 1.71e-104: 359: 30.73		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Hs
		674566 UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		411526 INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		213488 UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		195987 PLXB1_HUMAN (522-1068): 1.81e-42: 173: 17.96		SGTB_HUMAN (70-177): 7.78e-10: 60.8: 18.52
+	Hs
		850493 PLXA3_HUMAN (375-943): 1.56e-37: 156: 21.35		SGTB_HUMAN (70-177): 7.78e-10: 60.8: 18.52