HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: SHRM2 (Q13796)
Protein Shroom2 (Apical-like protein) (Protein APXL)
Gene: SHROOM2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17979178
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1616
+	Hs
		909543 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		SHRM2_HUMAN (1-1616): 2.67e-179: 583: 100.00
+	Hs
		904542 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		SHRM2_HUMAN (1-1616): 2.67e-179: 583: 100.00
+	Hs
		909464 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		DYST_HUMAN (1301-1609): 8.81e-52: 204: 13.88
+	Hs
		910159 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		MACF1_HUMAN (1275-1606): 3.64e-49: 196: 13.17
+	Hs
		904463 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		DYST_HUMAN (1301-1609): 8.81e-52: 204: 13.88
+	Hs
		974059 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		DYST_HUMAN (1301-1609): 8.81e-52: 204: 13.88
+	Hs
		905261 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		MACF1_HUMAN (1275-1606): 3.64e-49: 196: 13.17
+	Hs
		904629 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		SHRM1_HUMAN (875-1610): 1.23e-32: 139: 16.62
+	Mm
		935586 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		PDLI2_MOUSE (27-324): 9.72e-36: 142: 20.78
+	Hs
		982064 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		SHRM1_HUMAN (875-1610): 1.23e-32: 139: 16.62
+	Hs
		909854 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		SHRM3_HUMAN (1-1452): 2.45e-27: 123: 13.11
+	Hs
		904909 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		SHRM3_HUMAN (1-1452): 2.45e-27: 123: 13.11
+	Hs
		982320 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		SHRM3_HUMAN (1-1452): 2.45e-27: 123: 13.11
+	Hs
		297821 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		K0754_HUMAN (284-838): 1.96e-21: 104: 9.17
+	Hs
		904565 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		NCOA6_HUMAN (108-1432): 5.03e-15: 83.2: 7.95
+	Hs
		910111 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		DAPLE_HUMAN (105-712): 1.06e-11: 72.3: 11.31
+	Hs
		982016 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		NCOA6_HUMAN (108-1432): 5.03e-15: 83.2: 7.95
+	Hs
		909455 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		ANK2_HUMAN (165-1513): 6.41e-09: 63.4: 10.39
+	Hs
		905200 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		DAPLE_HUMAN (105-712): 1.06e-11: 72.3: 11.31
+	Hs
		982568 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		DAPLE_HUMAN (105-712): 1.06e-11: 72.3: 11.31