HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: UBP54 (Q70EL1)
Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54)
Gene: USP54

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.50	0.630

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1684
+	Hs
		909723 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		UBP54_HUMAN (1-1684): 0: 2297: 100.00
+	Hs
		904761 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		UBP54_HUMAN (1-1684): 0: 2297: 100.00
+	Hs
		927205 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		UBP54_HUMAN (1-1684): 0: 2297: 100.00
+	Hs
		904760 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		UBP53_HUMAN (1-940): 4.81e-128: 430: 34.38
+	Hs
		982186 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		UBP53_HUMAN (1-940): 4.81e-128: 430: 34.38
+	Mm
		910244 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Hs
		905373 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Mm
		905335 1433G_MOUSE (1-246): 9.38e-138: 388: 86.99		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Zm
		22585 B6U284_MAIZE (4-245): 1.53e-139: 393: 59.43		A0A1D6I2F1_MAIZE (4-669): 1.97e-80: 291: 12.20
+	Mm
		935498 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Hs
		904415 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Hs
		905265 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		UBP22_HUMAN (2-352): 7.48e-85: 290: 15.42
+	Hs
		927542 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		UBP42_HUMAN (24-881): 5.02e-104: 366: 13.96
+	Hs
		259272 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		UBP12_HUMAN (8-353): 5.69e-86: 287: 16.85
+	Hs
		905377 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Hs
		982625 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		UBP22_HUMAN (2-352): 7.48e-85: 290: 15.42
+	Hs
		259277 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		UBP12_HUMAN (8-353): 5.69e-86: 287: 16.85
+	Mm
		926789 1433Z_MOUSE (3-245): 5.23e-108: 313: 74.49		UBP48_MOUSE (8-529): 1.18e-82: 297: 12.46
+	Hs
		905375 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		UBP46_HUMAN (7-353): 8.59e-87: 290: 16.53
+	Hs
		259266 1433B_HUMAN (3-245): 2.7e-107: 311: 75.51		UBP12_HUMAN (8-353): 5.69e-86: 287: 16.85