HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: RUSC2 (Q8N2Y8)
AP-4 complex accessory subunit RUSC2 (Interacting protein of Rab1) (Iporin) (RUN and SH3 domain-containing protein 2)
Gene: RUSC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 1516
+	Hs
		909804 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		RUSC2_HUMAN (1-1516): 0: 2699: 100.00
+	Hs
		904846 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		RUSC2_HUMAN (1-1516): 0: 2699: 100.00
+	Hs
		927295 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		RUSC2_HUMAN (1-1516): 0: 2699: 100.00
+	Hs
		683535 1433B_HUMAN (3-245): 2.7e-107: 311: 75.51		RUSC2_HUMAN (1-1516): 0: 2699: 100.00
+	Hs
		647100 1433T_HUMAN (3-245): 7.19e-106: 307: 71.43		RUSC2_HUMAN (1-1516): 0: 2699: 100.00
+	Hs
		684202 1433S_HUMAN (3-245): 2.76e-96: 283: 64.20		RUSC2_HUMAN (1-1516): 0: 2699: 100.00