HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: PI3R4 (Q99570)
Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein)
Gene: PIK3R4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1358
+	Hs
		909952 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		PI3R4_HUMAN (1-1358): 0: 1154: 100.00
+	Hs
		905029 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		PI3R4_HUMAN (1-1358): 0: 1154: 100.00
+	Hs
		910013 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		SIK2_HUMAN (10-996): 3.01e-151: 483: 12.43
+	Hs
		905098 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		SIK2_HUMAN (10-996): 3.01e-151: 483: 12.43
+	At
		1280891 14337_ARATH (2-244): 2.9e-141: 398: 59.18		CIPKC_ARATH (1-491): 3.68e-113: 366: 15.32
+	At
		788672 14333_ARATH (1-244): 1.01e-141: 398: 61.38		CIPKC_ARATH (1-491): 3.68e-113: 366: 15.32
+	At
		965360 14332_ARATH (4-244): 8.72e-141: 396: 60.91		CIPKC_ARATH (1-491): 3.68e-113: 366: 15.32
+	Mm
		935611 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		PLRG1_MOUSE (774-1358): 6.78e-113: 366: 13.78
+	Hs
		909532 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		KCC2D_HUMAN (24-470): 8.31e-101: 332: 14.91
+	Hs
		910174 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		KCC2A_HUMAN (24-470): 2.2e-98: 325: 15.35
+	Hs
		904532 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		KCC2D_HUMAN (24-470): 8.31e-101: 332: 14.91
+	At
		965300 14332_ARATH (4-244): 8.72e-141: 396: 60.91		PRL2_ARATH (811-1289): 1.52e-83: 284: 15.46
+	Mm
		910266 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		NUAK1_MOUSE (2-311): 1.93e-75: 266: 21.56
+	Hs
		229938 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		NUAK1_HUMAN (6-311): 7.6e-74: 262: 21.20
+	Hs
		229936 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		NUAK1_HUMAN (6-311): 7.6e-74: 262: 21.20
+	Hs
		229942 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		NUAK1_HUMAN (6-311): 7.6e-74: 262: 21.20
+	Hs
		910009 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		NUAK2_HUMAN (7-311): 1.51e-67: 242: 18.91
+	Hs
		883214 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		SIK1_HUMAN (26-333): 4.95e-60: 224: 17.98
+	Hs
		883212 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		SIK1_HUMAN (26-333): 4.95e-60: 224: 17.98
+	At
		788540 14333_ARATH (1-244): 1.01e-141: 398: 61.38		PRL1_ARATH (761-1189): 1.23e-13: 77.2: 12.47