HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: PKHA3 (Q9HB20)
Pleckstrin homology domain-containing family A member 3 (PH domain-containing family A member 3) (Phosphatidylinositol-four-phosphate adapter protein 1) (FAPP-1) (Phosphoinositol 4-phosphate adapter protein 1)
Gene: PLEKHA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 300
+	Hs
		910042 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		PKHA3_HUMAN (1-300): 5.99e-78: 241: 100.00
+	Hs
		905129 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		PKHA3_HUMAN (1-300): 5.99e-78: 241: 100.00
+	Hs
		909582 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		ACAP2_HUMAN (1-300): 6.71e-44: 161: 16.88
+	Hs
		927547 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		PKHA3_HUMAN (1-300): 5.99e-78: 241: 100.00
+	Hs
		909680 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	At
		788659 14333_ARATH (1-244): 1.01e-141: 398: 61.38		DRP2A_ARATH (3-287): 9.8e-38: 144: 16.27
+	Mm
		935568 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		OSB11_MOUSE (1-298): 2.08e-42: 157: 16.62
+	Hs
		904714 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		982141 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		910172 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		904575 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		ACAP1_HUMAN (1-221): 4.27e-35: 135: 14.46
+	Hs
		905067 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		OSB10_HUMAN (1-298): 7.33e-34: 132: 16.14
+	Hs
		905271 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		982447 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		OSB10_HUMAN (1-298): 7.33e-34: 132: 16.14
+	Hs
		982632 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		927168 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		683445 1433B_HUMAN (3-245): 2.7e-107: 311: 75.51		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		647001 1433T_HUMAN (3-245): 7.19e-106: 307: 71.43		PKHA7_HUMAN (1-296): 9.53e-39: 147: 14.95
+	Hs
		927669 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09
+	Hs
		683824 1433B_HUMAN (3-245): 2.7e-107: 311: 75.51		GAB2_HUMAN (3-264): 1.74e-33: 131: 14.09