HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 246 Hs			1 956
+	Hs
		910060 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		905148 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		927563 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		683740 1433B_HUMAN (3-245): 2.7e-107: 311: 75.51		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		647304 1433T_HUMAN (3-245): 7.19e-106: 307: 71.43		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		684342 1433S_HUMAN (3-245): 2.76e-96: 283: 64.20		CYLD_HUMAN (1-956): 0: 1872: 100.00