HitPredict

Interactor 1: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Interactor 2: HDAC5 (Q9UQL6)
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)
Gene: HDAC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	33961781, 35271311, 21081666, 23752268, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1122
+	Hs
		910173 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		905272 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Mm
		910239 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		Q3UJF1_MOUSE (1-1122): 0: 717: 92.71
+	Mm
		910352 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		HDAC5_MOUSE (1-1122): 0: 713: 92.17
+	Mm
		935495 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		Q3UJF1_MOUSE (1-1122): 0: 717: 92.71
+	Mm
		935719 1433F_MOUSE (1-246): 6.15e-136: 383: 99.19		HDAC5_MOUSE (1-1122): 0: 713: 92.17
+	Hs
		880661 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		880659 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		880691 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		910144 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC9_HUMAN (25-1055): 0: 608: 56.33
+	Hs
		880673 1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		909856 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC7_HUMAN (121-1122): 4.12e-159: 499: 40.82
+	Hs
		904911 1433G_HUMAN (1-246): 9.38e-138: 388: 86.99		HDAC7_HUMAN (121-1122): 4.12e-159: 499: 40.82
+	Hs
		982322 1433F_HUMAN (1-246): 6.09e-136: 383: 100.00		HDAC7_HUMAN (121-1122): 4.12e-159: 499: 40.82
+	Hs
		909530 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Mm
		910299 1433E_MOUSE (1-244): 1.37e-141: 398: 62.71		HDAC7_MOUSE (191-1122): 3.04e-139: 446: 37.55
+	Hs
		177251 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57
+	Dm
		664668 1433Z_DROME (3-242): 8.23e-108: 312: 73.33		Q9VYF3_DROME (113-1121): 4.18e-149: 480: 30.31
+	Dm
		664611 1433Z_DROME (3-242): 8.23e-108: 312: 73.33		Q59E49_DROME (135-1121): 3.58e-143: 463: 30.18
+	Hs
		910121 1433E_HUMAN (1-244): 1.37e-141: 398: 62.71		HDAC6_HUMAN (599-1061): 7.06e-106: 362: 31.97