HitPredict

Interactor 1: BRAF (Q04982)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)
Gene: BRAF

Interactor 2: 1433G (Q5F3W6)
14-3-3 protein gamma
Gene: YWHAG

Species: Gallus gallus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27034005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~C1_1, 14-3-3~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Gg			1 247
+	Gg
		982842 BRAF_CHICK (1-766): 0: 774: 100.00		1433E_CHICK (1-244): 1.45e-141: 398: 63.53
+	Gg
		982837 BRAF_CHICK (1-766): 0: 774: 100.00		Q5ZKJ2_CHICK (1-247): 8.41e-135: 381: 87.05
+	Hs
		542849 BRAF_HUMAN (1-766): 0: 754: 93.89		1433E_HUMAN (1-244): 1.45e-141: 398: 63.53
+	Hs
		542847 BRAF_HUMAN (1-766): 0: 754: 93.89		1433G_HUMAN (1-247): 3.19e-140: 394: 99.60
+	Hs
		110869 H7C560_HUMAN (1-763): 0: 748: 93.86		1433E_HUMAN (1-244): 1.45e-141: 398: 63.53
+	Hs
		542868 BRAF_HUMAN (1-766): 0: 754: 93.89		1433F_HUMAN (1-246): 2.39e-135: 382: 86.59
+	Hs
		46557 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433G_HUMAN (1-247): 3.19e-140: 394: 99.60
+	Mm
		655938 BRAF_MOUSE (9-766): 0: 713: 89.74		1433E_MOUSE (1-244): 1.45e-141: 398: 63.53
+	Hs
		46558 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433F_HUMAN (1-246): 2.39e-135: 382: 86.59
+	Mm
		655936 BRAF_MOUSE (9-766): 0: 713: 89.74		1433G_MOUSE (1-247): 3.19e-140: 394: 99.60
+	Gg
		982838 BRAF_CHICK (1-766): 0: 774: 100.00		1433B_CHICK (2-247): 5.3e-110: 318: 76.21
+	Gg
		982836 BRAF_CHICK (1-766): 0: 774: 100.00		1433Z_CHICK (2-245): 9.87e-109: 315: 74.59
+	Gg
		982840 BRAF_CHICK (1-766): 0: 774: 100.00		1433T_CHICK (2-245): 2.47e-106: 308: 71.14
+	Hs
		542827 BRAF_HUMAN (1-766): 0: 754: 93.89		1433B_HUMAN (2-247): 1.04e-109: 317: 75.40
+	Hs
		542857 BRAF_HUMAN (1-766): 0: 754: 93.89		1433Z_HUMAN (2-245): 8.01e-109: 315: 74.59
+	Hs
		110870 H7C560_HUMAN (1-763): 0: 748: 93.86		1433Z_HUMAN (2-245): 8.01e-109: 315: 74.59
+	Hs
		542820 BRAF_HUMAN (1-766): 0: 754: 93.89		1433T_HUMAN (2-245): 2.57e-105: 306: 70.33
+	Hs
		542828 BRAF_HUMAN (1-766): 0: 754: 93.89		1433S_HUMAN (2-245): 1.59e-98: 289: 65.16
+	Hs
		46556 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433B_HUMAN (2-247): 1.04e-109: 317: 75.40
+	Mm
		250867 BRAF_MOUSE (9-766): 0: 713: 89.74		1433S_MOUSE (2-236): 6.79e-96: 282: 65.96