HitPredict

Interactor 1: BRAF (Q04982)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)
Gene: BRAF

Interactor 2: Q5ZKJ2 (Q5ZKJ2)
14-3-3 domain-containing protein
Gene: RCJMB04_10g10

Species: Gallus gallus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27034005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~C1_1, 14-3-3~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Gg			1 247
+	Gg
		982842 BRAF_CHICK (1-766): 0: 774: 100.00		1433E_CHICK (1-244): 2.38e-141: 398: 62.71
+	Gg
		982833 BRAF_CHICK (1-766): 0: 774: 100.00		1433G_CHICK (1-247): 2.37e-138: 390: 87.05
+	Hs
		542849 BRAF_HUMAN (1-766): 0: 754: 93.89		1433E_HUMAN (1-244): 2.38e-141: 398: 62.71
+	Hs
		110869 H7C560_HUMAN (1-763): 0: 748: 93.86		1433E_HUMAN (1-244): 2.38e-141: 398: 62.71
+	Hs
		542847 BRAF_HUMAN (1-766): 0: 754: 93.89		1433G_HUMAN (1-247): 8.09e-138: 388: 87.45
+	Hs
		542868 BRAF_HUMAN (1-766): 0: 754: 93.89		1433F_HUMAN (1-246): 7.28e-135: 381: 97.97
+	Hs
		46557 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433G_HUMAN (1-247): 8.09e-138: 388: 87.45
+	Mm
		655938 BRAF_MOUSE (9-766): 0: 713: 89.74		1433E_MOUSE (1-244): 2.38e-141: 398: 62.71
+	Hs
		46558 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433F_HUMAN (1-246): 7.28e-135: 381: 97.97
+	Mm
		655936 BRAF_MOUSE (9-766): 0: 713: 89.74		1433G_MOUSE (1-247): 8.09e-138: 388: 87.45
+	Gg
		982836 BRAF_CHICK (1-766): 0: 774: 100.00		1433Z_CHICK (3-245): 1.61e-108: 314: 75.31
+	Gg
		982838 BRAF_CHICK (1-766): 0: 774: 100.00		1433B_CHICK (3-247): 5.58e-107: 310: 74.90
+	Gg
		982840 BRAF_CHICK (1-766): 0: 774: 100.00		1433T_CHICK (3-245): 9.55e-107: 310: 71.84
+	Hs
		542827 BRAF_HUMAN (1-766): 0: 754: 93.89		1433B_HUMAN (3-247): 7.73e-108: 312: 74.90
+	Hs
		542857 BRAF_HUMAN (1-766): 0: 754: 93.89		1433Z_HUMAN (3-245): 7.72e-108: 312: 74.49
+	Hs
		542820 BRAF_HUMAN (1-766): 0: 754: 93.89		1433T_HUMAN (3-245): 5.32e-106: 308: 71.43
+	Hs
		110870 H7C560_HUMAN (1-763): 0: 748: 93.86		1433Z_HUMAN (3-245): 7.72e-108: 312: 74.49
+	Hs
		542828 BRAF_HUMAN (1-766): 0: 754: 93.89		1433S_HUMAN (3-245): 1.73e-96: 284: 64.20
+	Hs
		46556 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433B_HUMAN (3-247): 7.73e-108: 312: 74.90
+	Mm
		250867 BRAF_MOUSE (9-766): 0: 713: 89.74		1433S_MOUSE (3-236): 1.02e-94: 279: 65.81