HitPredict

Interactor 1: BRAF (Q04982)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)
Gene: BRAF

Interactor 2: GRP75 (Q5ZM98)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9)
Gene: HSPA9

Species: Gallus gallus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27034005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005739 - mitochondrion
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 766 Gg			1 675
+	Gg
		251126 BRAF_CHICK (1-766): 0: 774: 100.00		HSP7C_CHICK (53-655): 0: 875: 49.51
+	Mm
		655932 BRAF_MOUSE (9-766): 0: 713: 89.74		GRP75_MOUSE (29-675): 0: 925: 93.11
+	Hs
		503368 BRAF_HUMAN (1-766): 0: 754: 93.89		HSP7C_HUMAN (53-655): 0: 881: 49.51
+	Hs
		542812 BRAF_HUMAN (1-766): 0: 754: 93.89		HSP76_HUMAN (51-673): 0: 875: 48.43
+	Hs
		542834 BRAF_HUMAN (1-766): 0: 754: 93.89		GRP75_HUMAN (21-674): 0: 855: 92.05
+	Mm
		655941 BRAF_MOUSE (9-766): 0: 713: 89.74		HSP7C_MOUSE (53-655): 0: 881: 49.51
+	Hs
		373593 RAF1_HUMAN (100-755): 0: 577: 54.33		HSP7C_HUMAN (53-655): 0: 881: 49.51
+	Hs
		373642 RAF1_HUMAN (100-755): 0: 577: 54.33		HSP76_HUMAN (51-673): 0: 875: 48.43
+	Hs
		374331 RAF1_HUMAN (100-755): 0: 577: 54.33		Q53FC7_HUMAN (51-673): 0: 870: 48.11
+	Hs
		373811 RAF1_HUMAN (100-755): 0: 577: 54.33		GRP75_HUMAN (21-674): 0: 855: 92.05
+	Hs
		488545 ARAF_HUMAN (143-750): 1.58e-165: 492: 55.88		HSP7C_HUMAN (53-655): 0: 881: 49.51
+	Hs
		488563 ARAF_HUMAN (143-750): 1.58e-165: 492: 55.88		HSP76_HUMAN (51-673): 0: 875: 48.43
+	Hs
		503499 EPHB2_HUMAN (101-748): 4.33e-154: 477: 18.40		HSP7C_HUMAN (53-655): 0: 881: 49.51
+	Hs
		488602 ARAF_HUMAN (143-750): 1.58e-165: 492: 55.88		GRP75_HUMAN (21-674): 0: 855: 92.05
+	Gg
		982845 BRAF_CHICK (1-766): 0: 774: 100.00		BIP_CHICK (55-622): 0: 558: 53.73
+	Mm
		588704 BRAF_MOUSE (9-766): 0: 713: 89.74		BIP_MOUSE (55-644): 0: 555: 51.16