HitPredict

Interactor 1: BRAF (Q04982)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)
Gene: BRAF

Interactor 2: 1433T (Q5ZMD1)
14-3-3 protein theta
Gene: YWHAQ

Species: Gallus gallus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27034005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~C1_1, 14-3-3~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 766 Gg			1 245
+	Gg
		982842 BRAF_CHICK (1-766): 0: 774: 100.00		1433E_CHICK (2-243): 1.58e-143: 403: 63.93
+	Gg
		982836 BRAF_CHICK (1-766): 0: 774: 100.00		1433Z_CHICK (1-245): 7.53e-140: 393: 80.00
+	Hs
		542849 BRAF_HUMAN (1-766): 0: 754: 93.89		1433E_HUMAN (2-243): 1.58e-143: 403: 63.93
+	Hs
		110869 H7C560_HUMAN (1-763): 0: 748: 93.86		1433E_HUMAN (2-243): 1.58e-143: 403: 63.93
+	Hs
		542820 BRAF_HUMAN (1-766): 0: 754: 93.89		1433T_HUMAN (1-245): 9.91e-141: 395: 98.78
+	Hs
		542857 BRAF_HUMAN (1-766): 0: 754: 93.89		1433Z_HUMAN (1-245): 1.7e-140: 395: 79.59
+	Hs
		110870 H7C560_HUMAN (1-763): 0: 748: 93.86		1433Z_HUMAN (1-245): 1.7e-140: 395: 79.59
+	Hs
		542827 BRAF_HUMAN (1-766): 0: 754: 93.89		1433B_HUMAN (1-242): 4.91e-138: 389: 82.23
+	Gg
		982838 BRAF_CHICK (1-766): 0: 774: 100.00		1433B_CHICK (1-242): 9.92e-127: 360: 81.41
+	Mm
		655938 BRAF_MOUSE (9-766): 0: 713: 89.74		1433E_MOUSE (2-243): 1.58e-143: 403: 63.93
+	Hs
		46556 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433B_HUMAN (1-242): 4.91e-138: 389: 82.23
+	Gg
		982837 BRAF_CHICK (1-766): 0: 774: 100.00		Q5ZKJ2_CHICK (2-242): 9.48e-107: 310: 71.84
+	Gg
		982833 BRAF_CHICK (1-766): 0: 774: 100.00		1433G_CHICK (1-242): 2.45e-106: 308: 71.14
+	Hs
		542828 BRAF_HUMAN (1-766): 0: 754: 93.89		1433S_HUMAN (1-236): 1.17e-106: 310: 71.01
+	Hs
		542868 BRAF_HUMAN (1-766): 0: 754: 93.89		1433F_HUMAN (2-242): 1.22e-106: 309: 71.84
+	Hs
		542847 BRAF_HUMAN (1-766): 0: 754: 93.89		1433G_HUMAN (1-242): 5.51e-106: 308: 71.14
+	Hs
		46558 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433F_HUMAN (2-242): 1.22e-106: 309: 71.84
+	Hs
		46557 A0A2R8Y8E0_HUMAN (1-763): 0: 725: 89.21		1433G_HUMAN (1-242): 5.51e-106: 308: 71.14
+	Mm
		655936 BRAF_MOUSE (9-766): 0: 713: 89.74		1433G_MOUSE (1-242): 5.51e-106: 308: 71.14
+	Mm
		250867 BRAF_MOUSE (9-766): 0: 713: 89.74		1433S_MOUSE (1-232): 2.39e-105: 306: 71.80