HitPredict

Interactor 1: RRP5 (Q05022)
rRNA biogenesis protein RRP5 (Ribosomal RNA-processing protein 5) (U3 small nucleolar RNA-associated protein RRP5) (U3 snoRNA-associated protein RRP5)
Gene: RRP5

Interactor 2: RRP45 (Q05636)
Exosome complex component RRP45 (Ribosomal RNA-processing protein 45)
Gene: RRP45

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	12150911, 37968396, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RNase_PH~S1
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1729 Sc			1 305
+	Sc
		982920 RRP5_YEAST (1-1729): 0: 1247: 100.00		RRP42_YEAST (5-247): 1.03e-35: 131: 13.10
+	Sc
		809585 RRP5_YEAST (1-1729): 0: 1247: 100.00		RRP41_YEAST (21-290): 4.39e-25: 102: 13.00
+	Hs
		1058042 RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89		EXOS4_HUMAN (15-291): 2.68e-46: 158: 11.31
+	Hs
		300226 PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16		EXOS8_HUMAN (8-285): 1.44e-79: 244: 26.34
+	Hs
		300147 PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16		EXOS7_HUMAN (5-298): 9.58e-72: 225: 20.60
+	Sa
		1151452 PNP_STAAR (475-680): 6.73e-24: 111: 15.24		PNP_STAAR (9-294): 2.85e-51: 181: 13.47
+	Ec
		393715 PNP_ECOLI (442-682): 4.04e-26: 118: 14.29		PNP_ECOLI (1-294): 4.65e-42: 155: 12.93