HitPredict

Interactor 1: RRP5 (Q05022)
rRNA biogenesis protein RRP5 (Ribosomal RNA-processing protein 5) (U3 small nucleolar RNA-associated protein RRP5) (U3 snoRNA-associated protein RRP5)
Gene: RRP5

Interactor 2: UTP21 (Q06078)
U3 small nucleolar RNA-associated protein 21 (U3 snoRNA-associated protein 21) (U three protein 21)
Gene: UTP21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	37968396, 23209026, 24239293
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome and 1 others more... GO:0032040 - small-subunit processome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1729 Sc			1 939
+	Sc
		982919 RRP5_YEAST (1-1729): 0: 1247: 100.00		UTP12_YEAST (11-323): 6.77e-59: 220: 10.06
+	Sc
		635641 RRP5_YEAST (1-1729): 0: 1247: 100.00		PWP2_YEAST (2-230): 8.49e-13: 74.6: 8.86
+	Hs
		903230 RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89		WDR5_HUMAN (616-781): 6.74e-26: 111: 14.97
+	Hs
		1058048 RRP5_HUMAN (35-1717): 4.59e-129: 448: 15.89		NLE1_HUMAN (653-785): 5.4e-17: 86.9: 9.70
+	Hs
		672800 CDC27_HUMAN (1106-1729): 6.38e-66: 243: 12.30		WDR5_HUMAN (616-781): 6.74e-26: 111: 14.97
+	Hs
		174768 OGT1_HUMAN (1295-1728): 5.36e-41: 167: 12.33		WDR5_HUMAN (616-781): 6.74e-26: 111: 14.97
+	Sp
		141996 CLF1_SCHPO (1299-1707): 3.47e-35: 146: 13.38		PRP46_SCHPO (260-570): 3.64e-11: 68.6: 15.31
+	Hs
		300095 PRP6_HUMAN (1487-1729): 4.01e-19: 96.3: 15.16		WDR5_HUMAN (616-781): 6.74e-26: 111: 14.97
+	Sp
		142003 SYF1_SCHPO (1462-1664): 1.59e-12: 74.7: 16.28		PRP46_SCHPO (260-570): 3.64e-11: 68.6: 15.31