HitPredict

Interactor 1: CSTF1 (Q05048)
Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)
Gene: CSTF1

Interactor 2: CSTF3 (Q12996)
Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77)
Gene: CSTF3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	11459828, 35177536
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005848 - mRNA cleavage stimulating factor complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 431 Hs			1 717
+	Hs
		1022304 SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50		CSTF3_HUMAN (1-717): 0: 654: 100.00
+	Hs
		1199241 FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75		PRP39_HUMAN (7-595): 5.14e-75: 257: 15.54
+	Hs
		903230 WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75		RRP5_HUMAN (3-377): 9.42e-29: 125: 13.73
+	Hs
		1058048 NLE1_HUMAN (247-429): 1.25e-46: 169: 18.48		RRP5_HUMAN (3-377): 9.42e-29: 125: 13.73
+	Hs
		174768 WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75		OGT1_HUMAN (17-302): 6.94e-18: 90.4: 13.24
+	Hs
		175177 TBL1R_HUMAN (4-293): 1.29e-53: 188: 12.68		OGT1_HUMAN (17-302): 6.94e-18: 90.4: 13.24
+	Hs
		903236 WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75		SART3_HUMAN (3-278): 3.26e-14: 78.5: 14.73
+	Hs
		300095 WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75		PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30
+	Hs
		1058000 SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50		RRP5_HUMAN (3-377): 9.42e-29: 125: 13.73
+	Hs
		1288293 SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50		CRNL1_HUMAN (69-574): 5.03e-29: 125: 15.20
+	Sp
		1015545 YIDC_SCHPO (215-428): 3.11e-46: 167: 16.14		PRP1_SCHPO (4-306): 2.75e-11: 69.2: 13.16
+	Dm
		571971 Q9VPL0_DROME (247-429): 5.54e-39: 145: 15.76		CRN_DROME (3-218): 1.36e-11: 70: 15.04
+	Sp
		224207 TUP11_SCHPO (287-429): 1.73e-30: 125: 17.48		CYC8_SCHPO (288-713): 1.7e-16: 86.2: 10.38
+	Hs
		1288323 SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50		SYF1_HUMAN (5-399): 1.04e-17: 89.7: 11.63
+	Hs
		300167 SMU1_HUMAN (253-429): 5.21e-28: 117: 19.02		PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30
+	Hs
		300229 SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50		PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30
+	Hs
		175300 PRP19_HUMAN (136-335): 3.89e-14: 76.3: 24.50		OGT1_HUMAN (17-302): 6.94e-18: 90.4: 13.24
+	Hs
		197022 PRP4_HUMAN (305-429): 8.1e-15: 78.2: 20.47		SART3_HUMAN (3-278): 3.26e-14: 78.5: 14.73
+	Hs
		300222 FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75		PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30
+	Hs
		196929 PRP4_HUMAN (305-429): 8.1e-15: 78.2: 20.47		PRP6_HUMAN (7-294): 2.02e-09: 63.1: 8.30