HitPredict

Interactor 1: CDC42 (Q05062)
Cell division control protein 42 homolog (CDC42Ce)
Gene: cdc-42

Interactor 2: Q17795 (Q17795)
CRIB domain-containing protein
Gene: wsp-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	19923324, 20501656
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PBD~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005938 - cell cortex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Ce			1 607
+	Ce
		975571 RAC1_CAEEL (1-191): 8.74e-83: 245: 70.68		Q17795_CAEEL (1-607): 1.26e-154: 459: 100.00
+	Ce
		104465 G5EBV3_CAEEL (2-191): 8.09e-80: 237: 60.53		Q17795_CAEEL (1-607): 1.26e-154: 459: 100.00
+	Hs
		126910 RHOQ_HUMAN (4-187): 3.27e-91: 266: 67.94		WASL_HUMAN (12-320): 2.36e-77: 256: 26.77
+	Hs
		126960 RHOJ_HUMAN (2-189): 5.52e-84: 248: 63.30		WASL_HUMAN (12-320): 2.36e-77: 256: 26.77
+	Hs
		126927 CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39		WASL_HUMAN (12-320): 2.36e-77: 256: 26.77
+	Hs
		564443 RHOQ_HUMAN (4-187): 3.27e-91: 266: 67.94		WASP_HUMAN (27-403): 3.06e-64: 221: 21.39
+	Dm
		776909 RAC1_DROME (1-191): 1.44e-78: 234: 68.75		Q9VAT0_DROME (13-605): 5.49e-74: 248: 25.12
+	Dm
		776938 CDC42_DROME (1-191): 1.28e-77: 231: 88.48		Q9VAT0_DROME (13-605): 5.49e-74: 248: 25.12
+	Hs
		790687 RHOJ_HUMAN (2-189): 5.52e-84: 248: 63.30		WASP_HUMAN (27-403): 3.06e-64: 221: 21.39
+	Hs
		790658 RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11		WASP_HUMAN (27-403): 3.06e-64: 221: 21.39
+	Hs
		790653 CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39		WASP_HUMAN (27-403): 3.06e-64: 221: 21.39
+	Hs
		545246 RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71		WASP_HUMAN (27-403): 3.06e-64: 221: 21.39
+	Hs
		840659 RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87		DYN2_HUMAN (146-477): 6.73e-37: 149: 13.58
+	Hs
		297840 RHOJ_HUMAN (2-189): 5.52e-84: 248: 63.30		K0754_HUMAN (135-476): 1.48e-20: 99: 12.07
+	Hs
		297823 RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11		K0754_HUMAN (135-476): 1.48e-20: 99: 12.07
+	Hs
		297827 RHOG_HUMAN (1-191): 5.85e-79: 235: 58.12		K0754_HUMAN (135-476): 1.48e-20: 99: 12.07
+	Hs
		297812 RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71		K0754_HUMAN (135-476): 1.48e-20: 99: 12.07
+	Hs
		297820 RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87		K0754_HUMAN (135-476): 1.48e-20: 99: 12.07
+	Hs
		195972 RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87		PLXB1_HUMAN (341-533): 1.76e-12: 72.7: 19.80
+	Hs
		867087 CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39		SC24C_HUMAN (362-535): 7.7e-09: 60.8: 20.86