HitPredict

Interactor 1: CDC42 (Q05062)
Cell division control protein 42 homolog (CDC42Ce)
Gene: cdc-42

Interactor 2: GDIR (Q20496)
Probable rho GDP-dissociation inhibitor (Rho GDI)
Gene: rhi-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10583406
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~Rho_GDI
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Ce			1 191
+	Hs
		854769 RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11		GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17
+	Mm
		925816 RAC1_MOUSE (1-191): 2.97e-81: 241: 69.11		GDIR1_MOUSE (6-191): 1.59e-95: 277: 38.71
+	Hs
		854771 RHOG_HUMAN (1-191): 5.85e-79: 235: 58.12		GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17
+	Hs
		854760 CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39		GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17
+	Hs
		545278 RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71		GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17
+	Rn
		901290 RHOA_RAT (5-191): 8.36e-78: 232: 52.41		GDIR1_RAT (6-191): 1.59e-95: 277: 38.71
+	Hs
		854763 RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87		GDIR1_HUMAN (6-191): 1.54e-95: 277: 38.17
+	Hs
		854851 RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11		GDIR2_HUMAN (12-191): 4.68e-91: 266: 42.22
+	Hs
		854852 RHOG_HUMAN (1-191): 5.85e-79: 235: 58.12		GDIR2_HUMAN (12-191): 4.68e-91: 266: 42.22
+	At
		1105129 RAC3_ARATH (2-180): 4.55e-84: 248: 57.54		GDIR_ARATH (8-191): 3.87e-85: 252: 35.68
+	Ce
		975573 RAC1_CAEEL (1-191): 8.74e-83: 245: 70.68		GDIR_CAEEL (1-191): 7.1e-87: 255: 100.00
+	Hs
		925561 RAC1_HUMAN (1-191): 2.97e-81: 241: 69.11		GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71
+	Hs
		545279 RAC2_HUMAN (1-191): 7.66e-78: 232: 67.71		GDIR2_HUMAN (12-191): 4.68e-91: 266: 42.22
+	Hs
		951270 RHOG_HUMAN (1-191): 5.85e-79: 235: 58.12		GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71
+	Hs
		894357 CDC42_HUMAN (1-191): 2.71e-78: 233: 86.39		GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71
+	Mm
		892713 RAC3_MOUSE (1-177): 5.96e-76: 227: 70.62		GDIR2_MOUSE (5-191): 7.55e-90: 263: 38.50
+	Hs
		900840 RHOA_HUMAN (5-191): 2.39e-77: 231: 51.87		GDIR3_HUMAN (10-191): 1.18e-87: 258: 35.71
+	Sc
		580337 CDC42_YEAST (1-191): 1.2e-77: 231: 76.44		GDIR_YEAST (2-191): 7.42e-75: 225: 34.52
+	Ca
		483031 CDC42_CANAL (1-191): 1.99e-76: 228: 76.44		Q5AND4_CANAL (16-190): 3.16e-68: 208: 38.71
+	Cl
		47354 RAC1_CANLF (1-191): 2.97e-81: 241: 69.11		A0A8I3N6C6_CANLF (6-191): 1.23e-58: 182: 27.96