HitPredict

Interactor 1: UBE3A (Q05086)
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
Gene: UBE3A

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29511261
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 875 Hs			1 306
+	Hs
		125217 WWP2_HUMAN (291-873): 0: 589: 24.72		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		125268 WWP2_HUMAN (291-873): 0: 589: 24.72		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		125122 WWP2_HUMAN (291-873): 0: 589: 24.72		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		125640 WWP2_HUMAN (291-873): 0: 589: 24.72		DAZP1_HUMAN (163-285): 3.6e-21: 94.6: 21.14
+	Hs
		125430 WWP2_HUMAN (291-873): 0: 589: 24.72		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		516643 ITCH_HUMAN (325-873): 0: 579: 24.78		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Sc
		765284 RSP5_YEAST (310-873): 0: 554: 25.85		SGN1_YEAST (116-301): 3.31e-32: 121: 25.00
+	Hs
		1290129 ITCH_HUMAN (325-873): 0: 579: 24.78		DAZP1_HUMAN (163-285): 3.6e-21: 94.6: 21.14
+	Hs
		789549 SMUF1_HUMAN (405-872): 1.32e-175: 528: 27.04		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		1047917 SMUF1_HUMAN (405-872): 1.32e-175: 528: 27.04		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15