HitPredict

Interactor 1: UBE3A (Q05086)
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
Gene: UBE3A

Interactor 2: MA7D2 (Q96T17)
MAP7 domain-containing protein 2
Gene: MAP7D2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 875 Hs			1 732
+	Hs
		983140 UBE3A_HUMAN (1-875): 0: 1058: 100.00		MA7D1_HUMAN (4-649): 2.82e-47: 182: 18.31
+	Hs
		125500 WWP2_HUMAN (291-873): 0: 589: 24.72		MA7D1_HUMAN (4-649): 2.82e-47: 182: 18.31
+	Hs
		125188 WWP2_HUMAN (291-873): 0: 589: 24.72		MERL_HUMAN (423-657): 3.92e-20: 97.1: 23.65
+	Dm
		54898 SUDX_DROME (326-872): 0: 574: 24.87		A1ZA72_DROME (7-668): 5.49e-21: 101: 10.79
+	Hs
		719588 NED4L_HUMAN (247-873): 0: 575: 22.52		MERL_HUMAN (423-657): 3.92e-20: 97.1: 23.65
+	Mm
		93277 E9PXB7_MOUSE (329-873): 0: 573: 24.75		TAOK2_MOUSE (200-674): 1.21e-17: 90: 11.36
+	Hs
		1052176 HERC5_HUMAN (153-873): 1.77e-175: 536: 23.20		MAP7_HUMAN (8-585): 4.61e-26: 116: 27.32
+	Hs
		1078893 ITCH_HUMAN (325-873): 0: 579: 24.78		ITSN1_HUMAN (399-547): 1.71e-09: 63.8: 25.15
+	Hs
		1264807 SMUF2_HUMAN (334-872): 0: 554: 24.79		TITIN_HUMAN (93-641): 5.91e-09: 61.9: 9.75
+	Hs
		719532 HUWE1_HUMAN (523-874): 5.96e-53: 203: 33.97		MERL_HUMAN (423-657): 3.92e-20: 97.1: 23.65