Interactor 1: UBE3A (Q05086)
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
Gene: UBE3A

Interactor 2: DISC1 (Q9NRI5)
Disrupted in schizophrenia 1 protein
Gene: DISC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 0.60 0.457

The method score is based on:

Property Details
Experiments unassigned1973
Identification Methods two hybrid fragment pooling approach
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0098978 - glutamatergic synapse
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 875
Hs

1 854
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024