HitPredict

Interactor 1: ARPC4 (F4JUL9)
Actin-related protein 2/3 complex subunit 4 (Actin-related protein C4) (Arp2/3 complex 20 kDa subunit) (p20-ARC)
Gene: ARPC4

Interactor 2: ARC2A (Q8LGI3)
Actin-related protein 2/3 complex subunit 2A (Actin-related protein C2A) (Arp2/3 complex 34 kDa subunit) (p34-ARC) (Protein DISTORTED TRICHOMES 2)
Gene: ARPC2A

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	17267444, 15086808
Identification Methods	two hybrid, fluorescent resonance energy transfer, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ARPC4~P34-Arc
Common GO terms	GO:0005737 - cytoplasm GO:0005885 - Arp2/3 protein complex GO:0030041 - actin filament polymerization GO:0034314 - Arp2/3 complex-mediated actin nucleation GO:0042995 - cell projection and 1 others more... GO:0051015 - actin filament binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 169 At			1 318
+	Hs
		168906 ARPC4_HUMAN (1-168): 4.12e-95: 274: 64.88		ARPC2_HUMAN (1-304): 1.2e-140: 401: 27.10
+	Dm
		1368035 Q9VMH2_DROME (1-168): 8.78e-94: 271: 61.91		ARPC2_DROME (1-307): 3.43e-140: 399: 27.07
+	Sc
		703306 ARPC4_YEAST (1-169): 1.52e-85: 250: 59.41		ARPC2_YEAST (1-294): 1.99e-114: 336: 29.78