HitPredict

Interactor 1: DYN1 (Q05193)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: DNM1

Interactor 2: NOSTN (Q8IVI9)
Nostrin (BM247 homolog) (Nitric oxide synthase traffic inducer) (Nitric oxide synthase trafficker) (eNOS-trafficking inducer)
Gene: NOSTRIN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	16234328
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 506
+	Hs
		983417 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN2_HUMAN (6-496): 8.61e-55: 193: 15.22
+	Hs
		983405 DYN1_HUMAN (1-864): 0: 1087: 100.00		SH3G2_HUMAN (132-497): 6.08e-50: 176: 18.77
+	Rn
		192355 DYN1_RAT (1-864): 0: 1081: 98.03		SH3G3_RAT (132-500): 7.17e-50: 176: 17.11
+	Mm
		760455 DYN1_MOUSE (1-845): 0: 1081: 99.65		SH3G3_MOUSE (132-497): 9.8e-50: 175: 17.52
+	Hs
		983372 DYN1_HUMAN (1-864): 0: 1087: 100.00		MYO1E_HUMAN (18-495): 2.3e-40: 158: 11.94
+	Hs
		983406 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN1_HUMAN (3-298): 1.18e-40: 153: 16.18
+	Hs
		983403 DYN1_HUMAN (1-864): 0: 1087: 100.00		FNBP1_HUMAN (12-384): 4.2e-38: 149: 16.05
+	Rn
		193636 DYN1_RAT (1-864): 0: 1081: 98.03		SH3G1_RAT (132-500): 1.44e-41: 154: 18.09
+	Mm
		760453 DYN1_MOUSE (1-845): 0: 1081: 99.65		SH3G1_MOUSE (132-500): 3.84e-41: 153: 18.35
+	Rn
		599414 DYN1_RAT (1-864): 0: 1081: 98.03		PACN1_RAT (3-298): 4.14e-40: 152: 16.83
+	Mm
		760451 DYN1_MOUSE (1-845): 0: 1081: 99.65		PACN1_MOUSE (3-298): 6e-40: 151: 16.83
+	Hs
		983404 DYN1_HUMAN (1-864): 0: 1087: 100.00		SH3G1_HUMAN (132-500): 7.33e-38: 144: 19.20
+	Rn
		192351 DYN1_RAT (1-864): 0: 1081: 98.03		SH3G2_RAT (132-495): 3.37e-19: 90.7: 18.72
+	Mm
		760454 DYN1_MOUSE (1-845): 0: 1081: 99.65		SH3G2_MOUSE (132-495): 1.02e-18: 89.6: 18.98
+	Hs
		983399 DYN1_HUMAN (1-864): 0: 1087: 100.00		SH3K1_HUMAN (445-506): 1.13e-14: 78.8: 35.94
+	Hs
		983416 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN3_HUMAN (110-493): 3.58e-14: 76.4: 12.06
+	Mm
		760462 DYN1_MOUSE (1-845): 0: 1081: 99.65		SH3K1_MOUSE (404-495): 2.83e-14: 77.6: 32.26
+	Hs
		983379 DYN1_HUMAN (1-864): 0: 1087: 100.00		ITSN1_HUMAN (424-504): 3.46e-09: 61.8: 25.58
+	Rn
		599413 DYN1_RAT (1-864): 0: 1081: 98.03		ITSN1_RAT (342-504): 3.23e-09: 61.8: 17.86
+	Mm
		760469 DYN1_MOUSE (1-845): 0: 1081: 99.65		ITSN1_MOUSE (342-504): 4.6e-09: 61.4: 17.86