HitPredict

Interactor 1: DYN1 (Q05193)
Dynamin-1 (EC 3.6.5.5) (Dynamin) (Dynamin I)
Gene: DNM1

Interactor 2: PACN2 (Q9UNF0)
Protein kinase C and casein kinase substrate in neurons protein 2 (Syndapin-2) (Syndapin-II) (SdpII)
Gene: PACSIN2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11082044
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0050804 - modulation of chemical synaptic transmission GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 864 Hs			1 486
+	Hs
		983406 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN1_HUMAN (1-485): 3.17e-82: 263: 61.73
+	Rn
		599414 DYN1_RAT (1-864): 0: 1081: 98.03		PACN1_RAT (1-485): 4.7e-81: 260: 61.44
+	Mm
		760451 DYN1_MOUSE (1-845): 0: 1081: 99.65		PACN1_MOUSE (1-485): 5.4e-81: 260: 61.24
+	Mm
		760487 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN2_MOUSE (1-486): 2.43e-101: 314: 93.83
+	Hs
		983416 DYN1_HUMAN (1-864): 0: 1087: 100.00		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		840812 DYN2_HUMAN (1-860): 0: 1021: 78.91		PACN1_HUMAN (1-485): 3.17e-82: 263: 61.73
+	Mm
		760475 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN1_MOUSE (1-485): 5.4e-81: 260: 61.24
+	Hs
		983392 DYN1_HUMAN (1-864): 0: 1087: 100.00		NOSTN_HUMAN (24-485): 3.12e-47: 172: 16.13
+	Mm
		760485 DYN2_MOUSE (1-860): 0: 1022: 79.13		PACN3_MOUSE (6-485): 3.11e-69: 228: 43.54
+	Hs
		983403 DYN1_HUMAN (1-864): 0: 1087: 100.00		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Hs
		840860 DYN2_HUMAN (1-860): 0: 1021: 78.91		PACN3_HUMAN (6-485): 8.44e-67: 222: 41.04
+	Hs
		983372 DYN1_HUMAN (1-864): 0: 1087: 100.00		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		207784 DYN2_HUMAN (1-860): 0: 1021: 78.91		PPIP1_HUMAN (9-485): 2.02e-55: 192: 18.67
+	Hs
		840753 DYN2_HUMAN (1-860): 0: 1021: 78.91		FCSD1_HUMAN (26-481): 9.28e-47: 174: 14.79
+	Hs
		840700 DYN2_HUMAN (1-860): 0: 1021: 78.91		CIP4_HUMAN (12-465): 9.47e-47: 173: 15.03
+	Hs
		840798 DYN2_HUMAN (1-860): 0: 1021: 78.91		FNBP1_HUMAN (12-397): 7.86e-42: 159: 15.01
+	Mm
		760473 DYN2_MOUSE (1-860): 0: 1022: 79.13		SRC8_MOUSE (47-484): 1.33e-40: 154: 12.17
+	Hs
		840683 DYN2_HUMAN (1-860): 0: 1021: 78.91		MYO1E_HUMAN (9-485): 6.43e-38: 149: 13.04
+	Hs
		840692 DYN2_HUMAN (1-860): 0: 1021: 78.91		SRC8_HUMAN (47-484): 5.84e-38: 147: 11.40
+	Hs
		840723 DYN2_HUMAN (1-860): 0: 1021: 78.91		FBP1L_HUMAN (300-482): 7.32e-09: 60.2: 19.05