Interactor 1: MAD1 (Q05195)
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
Gene: MXD1

Interactor 2: MAD4 (Q14582)
Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4)
Gene: MXD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29028833
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005654 - nucleoplasm
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 221
Hs

1 209
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024