Interactor 1: FAK1 (Q05397)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2

Interactor 2: FAK1 (Q05397)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein phosphatase 1 regulatory subunit 71) (PPP1R71) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: PTK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 8816475, 25391654, 16141199, 12005431, 24480479
Identification Methods enzymatic study, pull down, x-ray crystallography
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_M~FERM_M, FERM_M~FERM_N_2, FERM_M~PK_Tyr_Ser-Thr, FERM_N_2~PK_Tyr_Ser-Thr, Focal_AT~Focal_AT, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0001525 - angiogenesis
GO:0001725 - stress fiber
GO:0001890 - placenta development
GO:0001932 - regulation of protein phosphorylation
GO:0001934 - positive regulation of protein phosphorylation
and 65 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1052
Hs

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Last updated: 15 Jul 2024