Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 8375396, 17639074, 29491746, 31980649, 21624955, 7588787, 11078718, 15665819
Identification Methods enzymatic study, affinity chromatography technology, in-gel kinase assay, protein kinase assay, mass spectrometry studies of complexes
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~Pkinase, PB1~PB1, PB1~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0000226 - microtubule cytoskeleton organization
GO:0001725 - stress fiber
GO:0001954 - positive regulation of cell-matrix adhesion
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
and 69 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 592
Hs

1 592
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Last updated: 15 Jul 2024