Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Interactor 2: RAGE (Q15109)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: AGER

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 21829704
Identification Methods anti tag coimmunoprecipitation, protein kinase assay, anti bait coimmunoprecipitation
Interaction Type physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0007166 - cell surface receptor signaling pathway
GO:0016324 - apical plasma membrane
GO:0030054 - cell junction
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 592
Hs

1 404
+ Mm

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Last updated: 15 Jul 2024