Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ
Interactor 2: KIBRA (Q8IX03)
Protein KIBRA (HBeAg-binding protein 3) (Kidney and brain protein) (KIBRA) (WW domain-containing protein 1)
Gene: WWC1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.88 | 1.00 | 0.938 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15081397, 28514442, 31980649, 33961781, unassigned2173 |
| Identification Methods | two hybrid, pull down, affinity chromatography technology, enzymatic study, protein kinase assay, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~C2 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016477 - cell migration GO:0030010 - establishment of cell polarity GO:0048471 - perinuclear region of cytoplasm |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
