HitPredict

Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29491746
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0031982 - vesicle GO:0046872 - metal ion binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 449
+	Hs
		933411 KPCZ_HUMAN (1-592): 0: 688: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		428156 KPCZ_HUMAN (1-592): 0: 688: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933766 KPCZ_HUMAN (1-592): 0: 688: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		784079 KPCI_HUMAN (1-592): 0: 654: 69.87		TBB2B_HUMAN (1-440): 0: 697: 40.23
+	Hs
		681913 AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		1309526 KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		428041 AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		681781 AKT1_HUMAN (172-582): 1.55e-153: 451: 36.39		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		933377 KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		428478 KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		934009 KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		969108 KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		933175 KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		408596 KPCB_HUMAN (85-187): 1.04e-21: 101: 27.18		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		428148 KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933762 KPCE_HUMAN (6-196): 1.52e-27: 120: 19.02		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		397156 KPCG_HUMAN (116-180): 1.87e-10: 65.9: 36.92		TBB4B_HUMAN (1-437): 0: 697: 40.73