Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ
Interactor 2: PAR6B (Q9BYG5)
Partitioning defective 6 homolog beta (PAR-6 beta) (PAR-6B)
Gene: PARD6B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 33961781, 11260256, 14676191, 25852190, 27107012, 29491746, 32296183, 31980649, 32707033, 12887891, unassigned1304, unassigned2173 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, barcode fusion genetics two hybrid, validated two hybrid, coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PB1~PB1, PB1~Pkinase |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005923 - bicellular tight junction GO:0016324 - apical plasma membrane GO:0045197 - establishment or maintenance of epithelial cell apical/basal polarity and 3 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
