Interactor 1: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Interactor 2: PAR6A (Q9NPB6)
Partitioning defective 6 homolog alpha (PAR-6) (PAR-6 alpha) (PAR-6A) (PAR6C) (Tax interaction protein 40) (TIP-40)
Gene: PARD6A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 15254234, 11260256, 14676191, 12813044, 25852190, 16189514, 28514442, 27143478, 33961781, 10873802, 17057644, 17350623
Identification Methods pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PB1~PB1, PB1~Pkinase
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0016324 - apical plasma membrane
GO:0045197 - establishment or maintenance of epithelial cell apical/basal polarity
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 592
Hs

1 346
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
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+ Hs
+ Dm
+ Ce
+ Dm
+ Hs
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+ Mm
+ Mm
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024