HitPredict

Interactor 1: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 484 Hs			1 567
+	Hs
		1037914 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRPK3_HUMAN (27-567): 5.16e-140: 418: 100.00
+	Hs
		942609 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		833869 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		984115 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		625528 TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Hs
		942637 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		942845 TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		1264773 TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99		DYRK2_HUMAN (344-565): 4.02e-65: 224: 25.82
+	Hs
		554284 MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85		GSK3B_HUMAN (23-336): 1.58e-67: 226: 16.87
+	Hs
		833876 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		CLK2_HUMAN (60-227): 1.39e-63: 218: 32.54
+	Hs
		1037873 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Hs
		834025 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		833717 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		CLK1_HUMAN (405-566): 8.71e-11: 66.2: 26.01
+	Dm
		834203 Q9VL71_DROME (27-173): 1.3e-36: 143: 47.65		DOA_DROME (396-566): 7.94e-12: 70.1: 25.41
+	Hs
		834036 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		CLK3_HUMAN (396-565): 4.23e-12: 70.9: 25.97
+	Hs
		833730 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		CLK1_HUMAN (405-566): 8.71e-11: 66.2: 26.01