HitPredict

Interactor 1: PP13 (Q05547)
Serine/threonine-protein phosphatase alpha-3 isoform (EC 3.1.3.16)
Gene: Pp1-13C

Interactor 2: Q7KU01 (Q7KU01)
Phosphatase 1 nuclear targeting subunit, isoform D (Phosphatase 1 nuclear targeting subunit, isoform E)
Gene: PNUTS

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	17007873, 24204300, 14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 302 Dm			1 1135
+	Dm
		819210 PP11_DROME (1-301): 0: 543: 92.36		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		819214 PP11_DROME (1-301): 0: 543: 92.36		Q7KU01_DROME (1-1135): 2.29e-141: 457: 100.00
+	Dm
		984175 PP13_DROME (1-302): 0: 542: 100.00		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		524617 PP12_DROME (1-302): 0: 541: 93.71		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		524623 PP12_DROME (1-302): 0: 541: 93.71		Q7KU01_DROME (1-1135): 2.29e-141: 457: 100.00
+	Dm
		819262 PP1B_DROME (5-302): 0: 528: 85.57		Q70HU3_DROME (1-1135): 2.29e-141: 457: 99.91
+	Dm
		984187 PP13_DROME (1-302): 0: 542: 100.00		Q960J4_DROME (750-1135): 1.53e-71: 245: 100.00
+	Hs
		906092 PP1A_HUMAN (2-301): 0: 549: 91.67		PP1RA_HUMAN (4-558): 7.19e-34: 143: 16.01
+	Hs
		737988 PP1G_HUMAN (3-301): 0: 547: 91.64		PP1RA_HUMAN (4-558): 7.19e-34: 143: 16.01
+	Hs
		906568 PP1B_HUMAN (5-302): 0: 537: 88.93		PP1RA_HUMAN (4-558): 7.19e-34: 143: 16.01
+	Hs
		102367 PP1B_HUMAN (5-302): 0: 537: 88.93		G3V1L9_HUMAN (115-911): 3.86e-26: 118: 9.13
+	Hs
		906425 PP1B_HUMAN (5-302): 0: 537: 88.93		ZO1_HUMAN (115-911): 3.76e-26: 118: 9.13
+	Dm
		113980 PP1B_DROME (5-302): 0: 528: 85.57		M9PB30_DROME (425-1053): 4.57e-25: 115: 10.74
+	Ce
		821920 GLC7B_CAEEL (2-301): 0: 550: 89.67		MEL28_CAEEL (175-774): 2.03e-15: 84: 10.35
+	Hs
		905838 PP1A_HUMAN (2-301): 0: 549: 91.67		ANK2_HUMAN (230-722): 1.3e-14: 81.4: 17.22
+	Hs
		270586 PP1G_HUMAN (3-301): 0: 547: 91.64		MYCB2_HUMAN (238-696): 2.94e-12: 73.7: 19.83
+	Ce
		1090117 GLC7A_CAEEL (5-302): 0: 536: 86.58		MEL28_CAEEL (175-774): 2.03e-15: 84: 10.35
+	Hs
		905894 PP1A_HUMAN (2-301): 0: 549: 91.67		MDC1_HUMAN (84-1012): 1.13e-10: 68.5: 8.29
+	Hs
		738130 PP1G_HUMAN (3-301): 0: 547: 91.64		SRRM2_HUMAN (94-951): 9.58e-10: 65.5: 8.21
+	Dm
		115296 PP1B_DROME (5-302): 0: 528: 85.57		M9PEP8_DROME (114-882): 7.45e-11: 69.1: 7.92