HitPredict

Interactor 1: NMDZ1 (Q05586)
Glutamate receptor ionotropic, NMDA 1 (GluN1) (Glutamate [NMDA] receptor subunit zeta-1) (N-methyl-D-aspartate receptor subunit NR1) (NMD-R1)
Gene: GRIN1

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.550

Property	Details
Experiments	9670010
Identification Methods	biochemical, pull down
Interaction Type	association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005516 - calmodulin binding GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 938 Hs			1 2472
+	Mm
		434795 NMDZ1_MOUSE (1-938): 0: 936: 99.04		SPTA1_MOUSE (1-2472): 2.17e-161: 558: 54.20
+	Rn
		555251 GRIA4_RAT (4-888): 0: 691: 22.21		SPTN1_RAT (1-2472): 0: 713: 98.58
+	Hs
		1028137 NMDE2_HUMAN (4-938): 0: 661: 23.83		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		786733 GRIA2_HUMAN (5-856): 0: 661: 21.49		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		1018891 NMDE1_HUMAN (2-923): 0: 602: 24.00		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Mm
		434799 NMDE2_MOUSE (4-938): 0: 654: 23.63		SPTA1_MOUSE (1-2472): 2.17e-161: 558: 54.20
+	Mm
		723587 NMDZ1_MOUSE (1-938): 0: 936: 99.04		SPTB2_MOUSE (1408-2420): 1.22e-29: 132: 18.86
+	Mm
		723613 NMDZ1_MOUSE (1-938): 0: 936: 99.04		ACTN2_MOUSE (1843-2210): 5.15e-13: 77: 23.23
+	Rn
		723638 NMDZ1_RAT (1-938): 0: 936: 99.25		ACTN1_RAT (1862-2210): 1.85e-11: 72: 22.51
+	Hs
		211568 NMDZ1_HUMAN (1-938): 0: 935: 100.00		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Rn
		585221 GRIA4_RAT (4-888): 0: 691: 22.21		SPTN2_RAT (141-1939): 1e-65: 251: 20.44
+	Hs
		786728 GRIA2_HUMAN (5-856): 0: 661: 21.49		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Rn
		585223 GRIA4_RAT (4-888): 0: 691: 22.21		ACTN4_RAT (1843-2219): 3.3e-10: 67.8: 20.30
+	Mm
		963773 NMDE2_MOUSE (4-938): 0: 654: 23.63		ACTN2_MOUSE (1843-2210): 5.15e-13: 77: 23.23