HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 793 Hs			1 2725
+	Hs
		598077 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261246 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		598255 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		598391 MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		597987 MYH11_HUMAN (2-686): 1.62e-23: 109: 9.77		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261303 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		261212 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Dm
		1303393 MYSN_DROME (2-660): 2.34e-25: 115: 10.46		FLNA_DROME (758-2724): 0: 1012: 33.19
+	Hs
		211569 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		963299 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		211632 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		521484 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		211515 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		963381 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		963335 ITSN1_HUMAN (235-636): 6.18e-27: 120: 21.34		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		1078871 ITSN1_HUMAN (235-636): 6.18e-27: 120: 21.34		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		362884 MYH10_HUMAN (55-788): 1.22e-26: 119: 10.63		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Dm
		90591 MYSN_DROME (2-660): 2.34e-25: 115: 10.46		E1JGS7_DROME (2215-2724): 1.79e-66: 253: 21.30
+	Hs
		362883 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		551790 DESP_HUMAN (13-640): 3.03e-22: 105: 14.35		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78