HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding and 1 others more... GO:0051017 - actin filament bundle assembly
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 759
+	Hs
		1268111 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1355290 MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		725057 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1068694 PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		149389 CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		1343911 MYO5C_HUMAN (13-485): 5.4e-09: 62.2: 14.38		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		984618 CALD1_HUMAN (1-793): 4.35e-43: 169: 100.00		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		1186077 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		724893 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		MICA3_HUMAN (271-544): 5.7e-43: 170: 23.93
+	Hs
		150607 MY18A_HUMAN (9-628): 1.86e-28: 125: 15.98		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		149231 CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87		LIMD2_HUMAN (354-472): 1.27e-39: 144: 52.50
+	Hs
		150533 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		148128 CTRO_HUMAN (122-718): 1.01e-14: 81: 9.87		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		823397 GOGB1_HUMAN (5-752): 1.76e-17: 89.9: 10.43		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53