HitPredict

Interactor 1: CALD1 (Q05682)
Caldesmon (CDM)
Gene: CALD1

Interactor 2: AKT3 (Q9Y243)
RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase Akt-3) (Protein kinase B gamma) (PKB gamma) (RAC-PK-gamma) (STK-2)
Gene: AKT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 793 Hs			1 479
+	Hs
		681881 GRDN_HUMAN (28-793): 9.97e-36: 148: 12.77		AKT1_HUMAN (1-477): 0: 558: 82.29
+	Mm
		682109 GRDN_MOUSE (28-793): 4.41e-34: 143: 12.52		AKT1_MOUSE (1-477): 0: 562: 82.08
+	Mm
		1130947 GRDN_MOUSE (28-793): 4.41e-34: 143: 12.52		AKT2_MOUSE (1-479): 0: 557: 75.57
+	Hs
		682219 MYO5A_HUMAN (42-632): 2.15e-24: 112: 15.29		AKT2_HUMAN (1-479): 0: 561: 75.78
+	Hs
		551616 DESP_HUMAN (13-640): 3.03e-22: 105: 14.35		AKT1_HUMAN (1-477): 0: 558: 82.29
+	Hs
		681696 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		AKT1_HUMAN (1-477): 0: 558: 82.29
+	Hs
		234193 PEPL_HUMAN (15-671): 2.36e-17: 89.5: 8.61		AKT1_HUMAN (1-477): 0: 558: 82.29
+	Mm
		682130 PEPL_MOUSE (27-700): 2.01e-12: 73.3: 10.60		AKT1_MOUSE (1-477): 0: 562: 82.08
+	Mm
		554901 MYH6_MOUSE (1-792): 7.67e-30: 129: 10.87		KPCE_MOUSE (52-473): 4.24e-148: 441: 39.58
+	Dm
		397193 MYSN_DROME (2-660): 2.34e-25: 115: 10.46		KPC1_DROME (13-476): 4.64e-152: 450: 35.48
+	Hs
		116964 MYH1_HUMAN (1-788): 6.51e-31: 133: 10.82		SGK1_HUMAN (100-477): 4.38e-147: 428: 45.12
+	Hs
		551672 DESP_HUMAN (13-640): 3.03e-22: 105: 14.35		KPCE_HUMAN (52-473): 1.57e-148: 443: 41.41
+	Hs
		724784 MYH9_HUMAN (2-631): 8.69e-22: 103: 10.87		KPCE_HUMAN (52-473): 1.57e-148: 443: 41.41
+	Hs
		254504 ROCK2_HUMAN (1-685): 2.36e-23: 108: 9.77		SGK3_HUMAN (61-479): 4.68e-149: 436: 42.35
+	Hs
		623875 PLEC_HUMAN (5-781): 2.36e-17: 89.5: 9.94		KPCL_HUMAN (110-476): 8.45e-151: 447: 41.73
+	Hs
		254459 ROCK2_HUMAN (1-685): 2.36e-23: 108: 9.77		KS6A3_HUMAN (146-418): 7.07e-101: 320: 28.52