HitPredict

Interactor 1: HMGD (Q05783)
High mobility group protein D (HMG-D)
Gene: HMGD

Interactor 2: FOXO (Q95V55)
Forkhead box protein O (dFOXO) (Protein FKHR)
Gene: FOXO

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27626673
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 112 Dm			1 613
+	Hs
		817928 SOX2_HUMAN (2-103): 4.13e-31: 113: 21.15		FOXK2_HUMAN (12-467): 2.59e-56: 203: 18.03
+	Hs
		964234 CIC_HUMAN (3-105): 2.36e-28: 109: 20.95		FOXK2_HUMAN (12-467): 2.59e-56: 203: 18.03
+	Hs
		817922 SOX2_HUMAN (2-103): 4.13e-31: 113: 21.15		FOXK1_HUMAN (20-441): 9.5e-52: 191: 18.74
+	Hs
		727724 SOX5_HUMAN (4-103): 4.45e-29: 111: 19.61		FOXK1_HUMAN (20-441): 9.5e-52: 191: 18.74
+	Hs
		952856 CIC_HUMAN (3-105): 2.36e-28: 109: 20.95		FOXK1_HUMAN (20-441): 9.5e-52: 191: 18.74
+	Hs
		225725 SOX15_HUMAN (4-93): 1.32e-29: 107: 21.74		FOXK1_HUMAN (20-441): 9.5e-52: 191: 18.74
+	Ce
		1014613 EGL13_CAEEL (2-108): 6.2e-36: 128: 19.27		FKH6_CAEEL (95-359): 3.87e-46: 167: 21.22
+	Ce
		1088824 EGL13_CAEEL (2-108): 6.2e-36: 128: 19.27		PHA4_CAEEL (45-383): 1.28e-43: 165: 17.30
+	Dm
		685356 Q59DN5_DROME (4-103): 2.48e-32: 120: 20.59		CROC_DROME (73-392): 5.36e-46: 171: 17.56
+	Dm
		115537 M9PFG6_DROME (3-87): 5.43e-32: 117: 19.54		CROC_DROME (73-392): 5.36e-46: 171: 17.56
+	Hs
		877708 SSRP1_HUMAN (2-75): 9.79e-26: 101: 50.00		FOXA1_HUMAN (17-422): 1.3e-51: 186: 19.42
+	Ce
		1014609 SOX3_CAEEL (3-88): 1.78e-30: 109: 19.32		FKH6_CAEEL (95-359): 3.87e-46: 167: 21.22
+	Ce
		1014621 SEM2_CAEEL (2-112): 4.33e-28: 107: 16.67		FKH6_CAEEL (95-359): 3.87e-46: 167: 21.22
+	Ce
		1088837 SEM2_CAEEL (2-112): 4.33e-28: 107: 16.67		PHA4_CAEEL (45-383): 1.28e-43: 165: 17.30
+	Hs
		1342336 HM20A_HUMAN (2-112): 5.34e-26: 100: 20.35		FX4L1_HUMAN (51-314): 1.41e-45: 168: 19.78
+	Hs
		1021338 CIC_HUMAN (3-105): 2.36e-28: 109: 20.95		FOXL1_HUMAN (47-350): 1.94e-42: 158: 20.45
+	Hs
		1021354 HM20A_HUMAN (2-112): 5.34e-26: 100: 20.35		FOXL1_HUMAN (47-350): 1.94e-42: 158: 20.45
+	Hs
		236590 CIC_HUMAN (3-105): 2.36e-28: 109: 20.95		FOXD2_HUMAN (95-180): 8.38e-38: 148: 40.91
+	Hs
		1300929 CIC_HUMAN (3-105): 2.36e-28: 109: 20.95		FOXQ1_HUMAN (99-179): 1.21e-09: 62.8: 40.48
+	Hs
		1318644 HM20A_HUMAN (2-112): 5.34e-26: 100: 20.35		FOXQ1_HUMAN (99-179): 1.21e-09: 62.8: 40.48