Interactor 1: HRD3 (Q05787)
ERAD-associated E3 ubiquitin-protein ligase component HRD3 (HMG-CoA reductase degradation protein 3)
Gene: HRD3
Interactor 2: HRD1 (Q08109)
ERAD-associated E3 ubiquitin-protein ligase HRD1 (EC 2.3.2.27) (HMG-CoA reductase degradation protein 1) (RING-type E3 ubiquitin transferase HRD1)
Gene: HRD1
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.762 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11018054, 25428985, 16619026, 20005842, 19696741, 16873066, 28682307, 32327568, 19394298, 37968396, 37066402, 21074049, 11139575, 16429126 |
| Identification Methods | coimmunoprecipitation, cross-linking study, affinity chromatography technology, x-ray crystallography, protein complementation assay, 3D electron microscopy, molecular sieving, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000836 - Hrd1p ubiquitin ligase complex GO:0000838 - Hrd1p ubiquitin ligase ERAD-M complex GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
