Interactor 1: HRD3 (Q05787)
ERAD-associated E3 ubiquitin-protein ligase component HRD3 (HMG-CoA reductase degradation protein 3)
Gene: HRD3
Interactor 2: OS9 (Q99220)
Protein OS-9 homolog
Gene: YOS9
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.90 | 0.916 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16873066, 16873065, 16845381, 37968396, 22262864, 25428985, 32327568 |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Sel1~Yos9_DD |
| Common GO terms | GO:0000836 - Hrd1p ubiquitin ligase complex GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex GO:0002235 - detection of unfolded protein GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane and 4 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
