HitPredict

Interactor 1: D6KL3 (Q05999)
Serine/threonine-protein kinase D6PKL3 (EC 2.7.11.1) (D6 protein kinase-like 3) (Serine/threonine-protein kinase AtPK7)
Gene: D6PKL3

Interactor 2: PDPK1 (Q9XF67)
3-phosphoinositide-dependent protein kinase 1 (AtPDK1) (EC 2.7.11.1)
Gene: PDPK1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.749

Property	Details
Experiments	16973627
Identification Methods	pull down, in-gel kinase assay
Interaction Type	direct interaction, physical association, enzymatic reaction

Property	Details
Interacting Pfam domains	Pkinase~Pkinase
Common GO terms	GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016301 - kinase activity and 1 others more... GO:0106310 - protein serine kinase activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 578 At			1 491
+	At
		1352858 D6KL1_ARATH (67-578): 7.29e-145: 429: 59.42		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		248799 PID_ARATH (106-558): 9.65e-138: 409: 42.46		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1247584 Q8RY37_ARATH (14-578): 5.34e-125: 387: 46.43		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		95768 RHS3_ARATH (72-578): 4.58e-128: 386: 48.43		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1322853 D6PK_ARATH (77-578): 3.83e-127: 384: 59.65		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1107155 D6KL2_ARATH (26-578): 4.23e-124: 379: 54.72		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1339696 AGC15_ARATH (1-578): 5.61e-124: 378: 44.20		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1340847 Q9M1P3_ARATH (182-527): 4.57e-125: 377: 49.07		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1339809 Q9LUK3_ARATH (67-578): 2.04e-121: 369: 53.13		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1093333 AGC17_ARATH (33-578): 3.29e-119: 365: 45.68		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1337841 KIPK1_ARATH (30-578): 2e-114: 363: 45.90		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1352414 KIPK2_ARATH (26-578): 7.98e-113: 360: 43.82		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1145519 PID2_ARATH (112-578): 8.45e-116: 355: 39.14		PDPK1_ARATH (1-491): 0: 523: 100.00
+	Sl
		1126590 Q5I6E9_SOLLC (2-578): 2.1e-121: 375: 50.94		Q5I6E8_SOLLC (2-491): 1.13e-170: 491: 80.61
+	At
		1339815 WAG2_ARATH (155-531): 1.56e-98: 309: 44.06		PDPK1_ARATH (1-491): 0: 523: 100.00
+	At
		1320801 WAG1_ARATH (155-544): 3.12e-94: 298: 41.35		PDPK1_ARATH (1-491): 0: 523: 100.00
+	Hs
		682034 LATS2_HUMAN (24-578): 1.75e-114: 367: 23.51		AKT1_HUMAN (2-372): 4.75e-146: 428: 31.10
+	Zm
		45132 A0A1D6QH07_MAIZE (171-510): 8.29e-120: 363: 18.03		A0A1D6QH07_MAIZE (33-491): 1.53e-141: 416: 23.03
+	Sc
		629516 KIN82_YEAST (13-575): 3e-111: 350: 28.69		FPK1_YEAST (26-325): 5e-58: 207: 40.00