HitPredict

Interactor 1: DEUP1 (Q05D60)
Deuterosome assembly protein 1 (Coiled-coil domain-containing protein 67)
Gene: DEUP1

Interactor 2: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 24613305, 28514442, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 604 Hs			1 1193
+	Hs
		1268075 CEP63_HUMAN (1-599): 2.25e-38: 152: 23.61		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		522657 MYH7_HUMAN (163-602): 8.15e-19: 93.4: 9.98		MYH4_HUMAN (291-1062): 2.67e-30: 132: 12.19
+	Hs
		1068639 CEP63_HUMAN (1-599): 2.25e-38: 152: 23.61		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		724969 CEP63_HUMAN (1-599): 2.25e-38: 152: 23.61		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		528435 MYH8_HUMAN (80-594): 8.33e-17: 87: 10.88		MYH4_HUMAN (291-1062): 2.67e-30: 132: 12.19
+	Hs
		149184 CEP63_HUMAN (1-599): 2.25e-38: 152: 23.61		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51
+	Rn
		361106 MYH6_RAT (163-602): 2.4e-17: 88.3: 10.38		MYH6_RAT (291-964): 6.07e-26: 118: 11.36
+	Hs
		528432 MYH8_HUMAN (80-594): 8.33e-17: 87: 10.88		MYH13_HUMAN (163-961): 2.75e-24: 113: 9.10
+	Hs
		522585 MYH7_HUMAN (163-602): 8.15e-19: 93.4: 9.98		MYH7_HUMAN (154-896): 6.03e-22: 105: 11.91
+	Mm
		93570 MYH9_MOUSE (56-603): 9.97e-24: 108: 9.42		DESP_MOUSE (501-1190): 4.1e-17: 89.6: 11.43
+	Hs
		1268126 MRCKB_HUMAN (16-458): 3.73e-24: 110: 14.43		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		724810 MYH9_HUMAN (15-494): 4.02e-20: 97.6: 8.21		ROCK1_HUMAN (546-1186): 1.44e-17: 90.8: 14.97
+	Hs
		724943 MYH9_HUMAN (15-494): 4.02e-20: 97.6: 8.21		MY18A_HUMAN (692-1192): 6.2e-16: 85.8: 13.78
+	Hs
		724895 MYH9_HUMAN (15-494): 4.02e-20: 97.6: 8.21		MYH14_HUMAN (449-1088): 6.07e-13: 75.8: 14.74
+	Hs
		724839 MYH9_HUMAN (15-494): 4.02e-20: 97.6: 8.21		PLEC_HUMAN (462-1139): 9.56e-12: 72: 14.40
+	Hs
		724687 MYH9_HUMAN (15-494): 4.02e-20: 97.6: 8.21		MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33
+	Hs
		724686 MYH9_HUMAN (15-494): 4.02e-20: 97.6: 8.21		MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04
+	Hs
		148460 MYH9_HUMAN (15-494): 4.02e-20: 97.6: 8.21		CTRO_HUMAN (356-721): 3.32e-10: 66.9: 9.51