HitPredict

Interactor 1: YTH1 (Q06102)
mRNA 3'-end-processing protein YTH1 (Yeast 30 kDa homolog 1)
Gene: YTH1

Interactor 2: YSH1 (Q06224)
Endoribonuclease YSH1 (EC 3.1.27.-) (Yeast 73 kDa homolog 1) (mRNA 3'-end-processing protein YSH1)
Gene: YSH1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.736

Property	Details
Experiments	11805826, 12626716, 16429126, 30737185, 16554755, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex GO:0006397 - mRNA processing GO:0030846 - termination of RNA polymerase II transcription, poly(A)-coupled and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 208 Sc			1 779
+	Hs
		317873 CPSF4_HUMAN (1-178): 1.31e-58: 187: 39.46		CPSF3_HUMAN (1-778): 0: 694: 37.21
+	Hs
		64099 CPS4L_HUMAN (1-167): 7.26e-50: 161: 35.06		CPSF3_HUMAN (1-778): 0: 694: 37.21
+	Sp
		142963 YTH1_SCHPO (4-174): 7.13e-42: 141: 38.37		YSH1_SCHPO (2-778): 0: 629: 47.11
+	Hs
		317868 CPSF4_HUMAN (1-178): 1.31e-58: 187: 39.46		CPSF2_HUMAN (6-729): 5.19e-127: 399: 18.13
+	At
		69150 CPSF_ARATH (12-117): 2.04e-14: 73: 23.36		CPS3B_ARATH (9-528): 1.23e-153: 463: 28.27
+	Sc
		985885 YTH1_YEAST (1-208): 5.83e-71: 216: 100.00		CFT2_YEAST (15-546): 2.92e-90: 304: 14.74
+	At
		69168 CPSF_ARATH (12-117): 2.04e-14: 73: 23.36		CPSF2_ARATH (6-446): 4.23e-121: 382: 23.83
+	Sp
		251804 YTH1_SCHPO (4-174): 7.13e-42: 141: 38.37		CFT2_SCHPO (26-546): 1.02e-86: 293: 18.00
+	Zm
		13939 A0A1D6FZC1_MAIZE (34-169): 1.04e-17: 82.6: 13.04		A0A1D6QRT7_MAIZE (2-537): 3.59e-90: 304: 15.39